VENTURA Cinzia Anna

Cinzia Anna Ventura – Curriculum Vitae
Born on 22/02/1964 in CATANIA

PRESENT POSITION
Since 2018, Full professor of Pharmaceutical Technology (SSD CHIM/09) at the Department of Chemical, Biological, Pharmaceutical and Environmental Sciences (CHIBIOFARAM), University of MESSINA.

PREVIOUS MAIN POSITIONS AND EDUCATION EXPERIENCES
- 2010-2018 Associate Professor of Pharmaceutical Technology (SSD CHIM/09) at the CHIBIOFARAM Department, University of MESSINA
- 2000-2010 Universitary researcher (SSD CHIM/09), Faculty of Pharmacy, University of MESSINA
- 1999 research grant in Pharmaceutical Technology, Faculty of Pharmacy, University of CATANIA
- 1997-1998 post-Doctoral scholarship in Pharmaceutical Sciences, Faculty of Pharmacy, University of CATANIA
- 1996 Volunteer, Faculty of Pharmacy, University of CATANIA
- 1994-1995 research collaboration contract funded by the Ministry of University and Scientific and Technological Research, University of CATANIA
- 1994 PhD in Pharmaceutical Sciences, University of CATANIA
- 1989 Qualification as pharmacist profession practice
- 1989 Degree in Pharmacy, 110/110 cum laude, University of CATANIA and Awards "Federfarma" and “Consorzio Catania Ricerche”

TEACHING ACTIVITY
Held courses since 2000 at MESSINA University for MSc Chemical and Technological Pharmaceuticals:
- Pharmaceutical Technology;
- National and UE Pharmaceutical Legislation.
Held courses since 2001 at MESSINA University for BSc Nutraceutical Sciences and Functional Foods
- Formulation and regulatory aspects of nutraceuticals and functional foods.
Since 2020 for the PhD school in Chemical Sciences at MESSINA University:
- Drug Delivery Systems.

RESEARCH ACTIVITY
The research activity concerns the development of:
- supramolecular carrier based on native and modified cyclodextrins for drug delivery;
- polymeric micro and nano-particles to improve physical-chemical property and targeting of drugs;
- lipid nanocarrier for drug delivery.
Author of 74 publications (71 ISI/Scopus), 11 oral presentations and 70 poster presentations to National and International Conferences.
Bibliometric data (SCOPUS-20/03/2022): Publications 71; Citations 2262; h-index 26.

RESEARCH PROJECTS
- Principal Investigator of a project selected and funded by CERIC (Central European Research Infrastructure Consortium), exp. n. 20157001. Project “Spatial disposition of hyaluronic acid in chitosan hyaluronan nanoparticles for drug delivery: a combined UV resonant Raman and microscopy study”. ELSFs: ELETTRA Sincrotrone Trieste. Budapest Neutron Center (BNC, H) (2016).
- -Beneficiary for the projects relating to the Funding of Basic University Research Activities (FFABR Unime) for year 2019 and 2021.
- Participant in:
- University Research Program (PRA) 2002-2005, “Drugs delivery by macromolecular, particulate and vesicular carrier”;
- PRA 2006-2007, "Interdisciplinary" project "Chemical-physical investigation of the structural and dynamic properties of carrier systems for drug delivery", 24 months;
- PRIN 2001, " Delivery and release of drugs in the central nervous system through lipid conjugates and colloidal systems ", 24 months;
- PRIN 2002, " Colloidal vesicular systems for the targeting of anticancer drugs ", 24 months;
- PRIN 2003, "Liposome formulations for the drug delivery in the treatment of neurodegenerative diseases ", 24 months;
- PRIN 2006, " Supramolecular lipid aggregates for anticancer agents delivery ", 24 months;
- PRIN 2010-2011, " Advanced technologies for the delivery of pharmacologically active molecules across the biological barriers ", 36 months.

COMPETENCES
ERC SECTORS
LS1_1 Macromolecular complexes including interactions involving nucleic acids, proteins, lipids and carbohydrates;
LS7_3 Nanomedicine
LS4_12 Cancer
PE4_2 Spectroscopic and spectrometric techniques

ORGANIZATION AND COORDINATION ACTIVITY:
- Member of the Scientific Committee of the 20 th International Cyclodextrin Symposium. Giardini Naxos (ME) Italy, June 13-17, 2022.
- Head of the Laboratory of Pharmaceutical Technology at the Dept. CHIBIOFARAM, Messina Univ..

EVALUATION ACTIVITY
- Reviewer for several international journals (Elsevier, Taylor & Francis, Springer, MDPI)

EDITORIAL ACTIVITY
Guest Editor of the Special Issues:
- "Nanosystems in Pharmaceutical Technology" for Molecules journal (ISSN 1420-3049), MDPI.
- "Women in Pharmaceutics" for Pharmaceutics journal (ISSN 1999-4923), MDPI.
- “Characterization and Biological Evaluation of Modified Drug Delivery Systems” for Applied Sciences journal (ISSN 2076-3417), MDPI.

INSTITUTIONAL ACTIVITY
- Board Member of the PhD in Chemical Sciences, and of the Specialization School in Hospital Pharmacy, University of MESSINA
- Member of the Quality Assurance Commission for the MSc Chemical and Technological Pharmaceutical
- President of the Commission for the qualification to Profession of Pharmacist - I and II session 2017 (MIUR Decree of 26.05.2017 and D.R. 1248/17).

10 SCIENTIFIC ARTICLES MOST CITED (SCOPUS)
1. Musumeci T., Ventura C.A., Giannone, I., Ruozi, B. Montenegro, L., Pignatello, R. Puglisi, G., PLA/PLGA nanoparticles for sustained release of docetaxel. Int. J. Pharm. 2006; 325, 172-179. Cited by 342.
2. Paolino, D., Ventura, C.A., Nisticò, S., Puglisi, G., Fresta, M., Lecithin microemulsions for the topical administration of ketoprofen: percutaneous adsorption through human skin and in vivo human skin tolerability. Int. J. Pharm., 2002; 244, 21-31. Cited by 180.
3. Celia, C., Trapasso, E., Locatelli, M., Navarra, M., Ventura, C.A., Wolfram, J., Carafa, M., Morittu, V.M., Britti, D., Di Marzio, L., Paolino, D., Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells.. Colloids Surf. B, Biointerfaces, 2013; 112, 548-553. Cited by 104.
4. Cosco, D., Paolino, D., Maiuolo, J., Di Marzio, L., Carafa, M., Ventura, C.A., Fresta, M., Ultradeformable liposomes as multidrug carrier of resveratrol and 5-fluorouracil for their topical delivery. Int. J. Pharm., 2015; 489, 1-10. Cited by 103
5. Venuti, V., Cannavà, C., Cristiano, M.C., Fresta, M. Majolino, D., Paolino, D., Stancanelli, R., Tommasini, S., Ventura, C.A. A characterization study of resveratrol/sulfobutylether-b-cyclodextrin inclusion complex and in vitro anticancer activity. Colloids Surf. B, Biointerfaces, 2014; 115, 22-28. Cited by 87
6. Ventura, C.A., Giannone, I., Paolino, D., Pistarà, V., Corsaro, A., Puglisi, G., Preparation of celecoxib-dimethyl-beta-cyclodextrin inclusion complex: characterization and in vitro permeation study. Eur. J. Med. Chem., 2005; 40, 624-631. Cited by 68
7. Ventura, C.A., Tommasini, S., Crupi, E., Giannone, I., Cardile, V., Musumeci, T., Puglisi, G. Chitosan microspheres for intrapulmonary administration of moxifloxacin: interaction with biomembrane models and in vitro permeation studies. Eur. J. Pharm. Biopharm., 2008; 68, 235-244. Cited by 65
8. Ventura, C.A., Tommasini, S., Falcone, A., Giannone, I., Paolino, D., Sdrafkakis, V., Mondello, M.R., Puglisi, G. Influence of modified cyclodextrins on solubility and percutaneous absorption of celecoxib through human skin. Int. J. Pharm., 2006; 314, 37-45. Cited by 61
9. Montenegro, L., Carbone, C., Maniscalco, C., Lambusta, D., Nicolosi, G., Ventura, C.A., Puglisi, G., In vitro evaluation of quercetin-3-O-acyl esters as topical prodrugs. Int. J. Pharm., 2007; 336, 257-262. Cited by 60
10. Gentile, E., Cilurzo, F., Di Marzio, L., Carafa, M., Ventura, C.A., Wolfram, J., Paolino, D., Celia, C. Liposomal Chemotherapeutics. Future Oncology, 2013; 9, 1849-1859. Cited by 55