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MACCARI Rosanna

Professoressa associata
Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali
Course Catalogue:
https://unime.coursecatalogue.cineca.it/docente-ma...

Gruppo 03/CHEM-07 - CHIMICA FARMACEUTICA, TOSSICOLOGICA, NUTRACEUTICO-ALIMENTARE, DELLE FERMENTAZIONI E DEI PRODOTTI PER IL BENESSERE E PER LA SALUTE

Settore CHEM-07/A - Chimica farmaceutica
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Description

Rosanna Maccari is an associate professor at the Department of Chemical, Biological, Pharmaceutical and Enviromental Sciences (ChiBioFarAm) of the University of Messina (Italy). She graduated in Medicinal Chemistry and in Pharmacy with first-class honours at the University of Messina. She did a Research Doctorate in Pharmaceutical Sciences at the University of Messina and was awarded a Ph.D. in 1997. She was a researcher of medicinal chemistry at the Faculty of Pharmacy, and then at the Department SCIFAR, of the University of Messina from 1999 to 2014. Since 2014 she has been an associate professor of medicinal chemistry. Since 1999 she has carried out teaching activity in medicinal chemistry subject courses at the Faculty of Pharmacy, then at the Department SCIFAR and now at Department ChiBioFarAm of the University of Messina. She has been tutor for students on degree and Ph.D. courses and supervisor of undergraduate experimental research and thesis preparation. She has been a member of the teaching body of the Ph.D. Courses in Medicinal Sciences and in Chemical Sciences at the University of Messina. She has been in charge of quality assurance of the degree course in Pharmacy of the University of Messina.
Rosanna Maccari is author of more than fifty scientific papers and one book chapter published in refereed international journals dealing with various aspects of medicinal chemistry and has made numerous presentations at national and international conferences.
Her main areas of expertise are: drug design, chemical synthesis, lead discovery and optimization in medicinal chemistry. Currently, her main research interests concern the design, synthesis, molecular modelling and structure/activity relationship studies of: a) protein tyrosine phosphatase inhibitors, as novel agents to fight insulin resistance and related pathologies; b) aldo-keto reductase inhibitors, to fight diabetic complications, cancer and inflammatory pathologies. In recent years she has also been engaged in the search for the identification of new antitubercular, anti-inflammatory, antitumoral and antiviral agents. She collaborates with Italian and Foreign research centres. She is an Editorial Board member of the international scientific journal Molecules. She is a reviewer for several international journals of medicinal chemistry. She is a member of the Italian Chemical Society. She has been a member of the executive board of the Sicily section of Italian Chemical Society.

Concepts (2)


PE5_18 - Medicinal chemistry - (2020)

Goal 3: Good health and well-being

Keywords

MEDICINAL CHEMISTRY
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Overview

Design, synthesis and the structure-activity relationship studies of potential therapeutic agents for the treatment of diabetes and associated complications. Design, synthesis and the structure-activity relationship studies of multi-target enzyme inhibitors aimed at the management of metabolic and inflammatory diseases.
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Collaborates with (2)

DESY LAB, Design and Synthesis Laboratory
Group
Medicinal chemistry research group
Group

Publications (122)

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Third Mission (2)

Attività di coinvolgimento e interazione con il mondo della scuola (Relatore/Relatrice) - Alla scoperta della ricerca farmaceutica: il ricercatore e la sua professione
Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali
Laboratori didattici Dip. ChiBioFarAm (17/12/2025 - 03/02/2026) 20251217
Attività di coinvolgimento e interazione con il mondo della scuola (Altro, Relatore/Relatrice) - Un giorno da Ricercatore
Dipartimento di Scienze matematiche e informatiche, scienze fisiche e scienze della terra
Dipartimento di Scienze chimiche, biologiche, farmaceutiche e ambientali
UNIVERSITA' DI MESSINA - POLO PAPARDO (10/05/2022 - 10/05/2022) 20220510
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Courses (2)

120 - DRUGS ANALYSIS II

Secondo Semestre (23/02/2026 - 29/05/2026) - 2025
10 CFU
90 hours

905 - MEDICINAL CHEMISTRY II

Primo Semestre (15/09/2025 - 19/12/2025) - 2025
10 CFU
66 hours
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