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Aggressive Angiomyxoma of the Vulva: Which Is the Best Management Strategy? Description of a Case Report and Review of Literature of the Last Ten Years

Articolo
Data di Pubblicazione:
2023
Abstract:
Background: Aggressive angiomyxoma is a rare mesenchymal tumour of the genital tract with a high incidence in women of reproductive age. The aim of our work is to understand which is the best management strategy for this condition, starting from the description of a rare case report up to the performance of a narrative review of the literature. Methods: We report a case of a 46-year-old woman who came to our attention because of the growth of a 10-centimetre pedunculated, non-soft, non-tender mass of the left labium majus. She underwent surgical excision, and the histologic diagnosis was aggressive angiomyxoma. Due to a lack of tumour-free margins, radicalization surgery was carried out after three months. A review of the literature of the last ten years was performed following the PRISMA statement on MEDLINE (PubMed). We obtained data from twenty-five studies describing thirty-three cases. Results: Aggressive angiomyxoma is characterized by a high recurrence rate of between 36 and 72% after surgery. There is no universal consensus about hormonal therapy, and most studies (85%) describe surgical excision followed by only clinical and radiological follow-up. Conclusion: Wide surgical excision is the gold-standard treatment for aggressive angiomyxoma, succeeded by either clinical or radiological (ultrasound or MRI) follow-up.
Tipologia CRIS:
14.a.1 Articolo su rivista
Keywords:
Aggressive angiomyxoma, genital tumour, mesenchymal tumour, vulvar lesion
Elenco autori:
Gulino, F. A.; Gulisano, M.; Ettore, C.; Giorlandino, A.; Russo, E.; Ettore, G.
Autori di Ateneo:
GULINO Ferdinando Antonio
Link alla scheda completa:
https://iris.unime.it/handle/11570/3275728
Link al Full Text:
https://iris.unime.it//retrieve/handle/11570/3275728/584401/Aggressive%20Angiomyxoma%20of%20the%20Vulva%20Which%20Is%20the%20Best%20Management%20Strategy%20Description%20of%20a%20Case%20Report%20and%20Review%20of%20Literature%20of%20the%20Last%20Ten%20Years.%20.pdf
Pubblicato in:
JOURNAL OF CLINICAL MEDICINE
Journal
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URL

https://www.mdpi.com/2077-0383/12/5/1726
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