Food-exercise-induced anaphylaxis in a boy successfully desensitized to cow milk.

It is well known that exercise can induce systemic reactions, even anaphylactic shock, in some patients suffering from food allergy. Typically, exercise-induced anaphylaxis occurs on exercise immediately after the ingestion of a specific food. Nonetheless, it can occur also in the postprandial state without the certain identification of a specific causative food. In addition, the occurrence of anaphylaxis when the responsible food is ingested immediately after the exercise has been described (1). Food-dependent exercise-induced anaphylaxis has been variously associated with cereals, seafood, peanuts, tree nuts, eggs, milk and vegetables. We describe herein a severe anaphylactic reaction after exercise and milk ingestion in a child who previously underwent a successful desensitization protocol for cow milk (CM) allergy We report herein, for the first time, a case of successful induction of tolerance to a food with the subsequent appearance of severe exercise-induced symptoms