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  1. Pubblicazioni

SARS-CoV-2 Infection in Patients with Cystic Fibrosis: What We Know So Far

Articolo
Data di Pubblicazione:
2022
Abstract:
Respiratory infections are the most common and most frequent diseases, especially in children and the elderly, characterized by a clear seasonality and with an incidence that usually tends to decrease with increasing age. These infections often resolve spontaneously, usually without the need for antibiotic treatment and/or with the possible use of symptomatic treatments aimed at reducing overproduction of mucus and decreasing coughing. However, when these infections occur in patients with weakened immune systems and/or underlying health conditions, their impact can become dramatic and in some cases life threatening. The rapid worldwide spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection has caused concern for everyone, becoming especially important for individuals with underlying lung diseases, such as CF patients, who have always paid close attention to implementing protective strategies to avoid infection. However, adult and pediatric CF patients contract coronavirus infection like everyone else. In addition, although numerous studies were published during the first wave of the pandemic on the risk for patients with cystic fibrosis (CF) to develop severe manifestations when infected with SARS-CoV-2, to date, a high risk has been found only for patients with poorer lung function and post-transplant status. In terms of preventive measures, vaccination remains key. The best protection for these patients is to strengthen preventive measures, such as social distancing and the use of masks. In this review, we aim to summarize and discuss recent advances in understanding the susceptibility of CF individuals to SARS-CoV-2 infection.
Tipologia CRIS:
14.a.1 Articolo su rivista
Keywords:
COVID-19; cystic fibrosis; viral infections
Elenco autori:
Biondo, Carmelo; Midiri, Angelina; Gerace, Elisabetta; Zummo, Sebastiana; Mancuso, Giuseppe
Autori di Ateneo:
BIONDO Carmelo
MANCUSO Giuseppe
MIDIRI Angelina
ZUMMO Sebastiana
Link alla scheda completa:
https://iris.unime.it/handle/11570/3251313
Pubblicato in:
LIFE
Journal
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