The role of transcranial direct current stimulation in patients with moderate cognitive decline

Cognitive decline comes with a significant change in cognitive performances. This change affects several cognitive domains, such as memory, attention, executive functions, perception, language, and psychomotor functions. The recent confirmation that neurogenesis occurs in the adult brain lead to hypothesize that non-invasive transcranial direct current stimulation (tDCS) might have a therapeutic potential in treating neurodegenerative diseases. The purpose of this study was to evaluate the effect of anodal tDCS on cognitive and neurophysiological functions inpatients with moderate cognitive impairment (MCI). Ten participants with moderate cognitive impairment underwent ten daily sessions of 2 mA tDCS over the left frontotemporal cortex. A pre-test-post test-follow up design was used to analyze the change in performance. Cognitive and neurophysiological assessments were administered before and after the tDCS sections. Results suggest that tDCS can improve cognitive and neurophysiological performance of patients with moderate cognitive decline