Publication Date:
2017
abstract:
The remarkable affinity of deca-carboxylatopillar[5] arene WP5 towards the aminoglycoside antibiotic, amikacin, in aqueous media is reported; in vitro studies on Gram-positive bacteria (Staphylococcus aureus) show that drug entrapment inside WP5 also takes place in the presence of the microrganisms, thus pointing to WP5 as an appealing carrier for amikacin targeted delivery.
Iris type:
14.a.1 Articolo su rivista
Keywords:
HOST-GUEST CHEMISTRY; SILICA NANOPARTICLES; BINDING; AMINOGLYCOSIDES; ENCAPSULATION; RECOGNITION; GENTAMICIN; RELEASE; ACID
List of contributors:
Barbera, Lucia; Franco, Domenico; De Plano, Laura Maria; Gattuso, Giuseppe; Guglielmino, Salvatore; Lentini, Germana; Manganaro, Nadia; Marino, Nino; Pappalardo, Sebastiano; Parisi, Melchiorre; Puntoriero, Fausto; Pisagatti, Ilenia; Notti, Anna
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