Sertoli cell tumors associated with feminizing syndrome and spermaticcord torsion in two cryptorchid dogs

The association of cryptorchidism, functional Sertoli cell
tumors, and spermatic cord torsion has been rarely
reported in the literature. Two dogs were admitted for
bilateral skin alopecia and weight loss. Both animals were
cryptorchid and displayed a pendulous preputial sheath,
prostate hypertrophy, and increased levels of circulating
oestrogen. Transabdominal palpation and ultrasonography
revealed the presence of neoplastic retained gonads. During
surgery, spermatic cord torsion was also detected in the
enlarged neoplastic testes of both dogs. Histologic
examination confirmed the presence of Sertoli cell tumors
that were primarily responsible for the feminizing
syndrome. Complete remission of all symptoms occurred
within 3 months after orchiectomy.