Stevens-Johnson syndrome after lenalidomide therapy for multiple myeloma: a case report and a review of treatment options.
Articolo
Data di Pubblicazione:
2012
Abstract:
Stevens‐ Johnson syndrome (SJS) is a severe and life-threatening condition. Although
allopurinol, an antihyperuricemia drug, is the drugmost commonly associatedwith SJS,more
than 100 different causative drugs have been reported. Among hematologic drugs recently
introduced into the market, drugs such as rituximab, imatinib, and bortezomib are reported.
Here, we describe a patient with SJS while receiving lenalidomide in combination with
prednisolone for treatment‐naïve multiple myeloma. Although SJS has been reported rarely
as an adverse reaction to Lenalidomide, this drug should be considered in the etiology of SJS,
and the increased number of prescriptions of Lenalidomide for the therapy of multiple
myeloma has to stress the awareness of its potentially serious side‐effects.
Tipologia CRIS:
14.a.1 Articolo su rivista
Keywords:
Lenalidomide; Stevens-Johnson syndrome; multiple myeloma; cutaneous adverse reaction
Elenco autori:
Allegra, Alessandro; Alonci, Andrea; Penna, G; Russo, S; Gerace, D; Greve, B; D'Angelo, A; Catena, S; Musolino, Caterina
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