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Can a call for prudence be simply alarmist?

Articolo
Data di Pubblicazione:
2009
Abstract:
Alzheimer’s disease is a growing global public health concern. Advanced research protocols to understand the pathogenesis of the molecular mechanisms of Alzheimer’s disease run parallel to dedicated research to determine the risk factors in this global scientific crusade. Detailed understanding of the underlying molecular mechanisms of this disease suggests that the amyloid beta peptide (Ab), hallmark of the disease, is subject to Ab oligomerization, a
process that increases synaptotoxicity. Increased aggregation of Ab through the stabilization of intermediate toxic oligomers is thought to contribute to neurocognitive dysfunction.
Tipologia CRIS:
14.a.1 Articolo su rivista
Keywords:
Alzheimer’s disease; Abeta-peptide; anaesthetics; molecular size; nuclear magnetic resonance spectroscopy; oligomerization; postoperative cognitive dysfunction.
Elenco autori:
Mandal, Pk; Fodale, Vincenzo
Autori di Ateneo:
FODALE Vincenzo
Link alla scheda completa:
https://iris.unime.it/handle/11570/1898511
Pubblicato in:
EUROPEAN JOURNAL OF ANAESTHESIOLOGY
Journal
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