Is a dangerous blood clot formation a reversible process? Introduction of new characteristic parameter for thermodynamic clot blood characterization: possible molecular mechanisms and pathophysiologic applications.

This paper focuses on the rheological characteristics of the blood clot using the non-equilibrium thermodynamics. The calculation of the phenomenological and state coefficients allowed to well characterize the clot showing its physical behavior at different frequencies. The goal of the study is to highlight an important inversion of the trend of physical behavior of the clot that tends to show fluidity characteristics for a certain frequency. A new coefficient has therefore been introduced which takes into account the viscoanelastic properties of the blood clot. A detailed focus on the rheology of the clot may help to solve or to prevent thrombus genesis in blood vessels.