Serum protein electrophoresis profile during late pregnancy and early post partum period in mares

The aim of the study was to determine how the physiological adjustments occurring during late pregnancy and the early post partum period affect mares’ serum protein profile. Ten pregnant mares (Group A) were monitored from the 34th week of pregnancy until the 3rd week after foaling, ten nonpregnant mares (Group B) were used as the control. Blood samples were collected every 3 weeks, from -16 to -4 weeks preceding parturition, and then every week until the 3rd week after foaling. Additional blood samples were taken within 24±12 h from foaling. The statistical analysis revealed a significant increase in albumin and α2-globulin concentrations obtained from Group A during the experimental period. Dunnet’s test also revealed significantly higher concentrations of α1-globulins, α2-globulins and γ-globulins in group A than in group B. The following results showed that the serum proteins differed in periparturient mares when compared to non-pregnant mares and significant changes in some protein fractions occurred over the experimental period. Focusing on the peripartum period, our study provides specific information about mare’s serum protein profile that could help equine practitioners to better interpret clinical data and promptly diagnose pathological conditions that might compromise the health status of the mare and, as consequence, also her foal.